What to Expect from the PharmaJet Needle-free Precision Delivery Systems
The spring-powered injectors deliver the vaccine or medicine by means of a narrow fluid stream, which penetrates the skin in about 1/10 of a second with a precise dose and depth. No external power source is required and there is no needle.
Like traditional injections, individuals will respond differently to the needle-free injection. Some feel nothing, while others have reported feeling the pressure of the injection or a snap like a rubber band when the injection is administered.
Yes. Both systems are validated and commercially available with regulatory clearances. The PharmaJet Tropis® System has CE Mark and WHO PQS certification for intradermal injections. The PharmaJet Stratis® System has U.S. FDA 510(k) marketing clearance, CE Mark, and WHO PQS certification to deliver pharmaceuticals either intramuscularly or subcutaneously.
No. Each needle-free syringe is sterile, auto disabling and cannot be reused.
PharmaJet partners report cost savings, improved injectable performance, and a high level of user satisfaction. Needle-free precision delivery technology significantly reduces patient fear and anxiety associated with getting a needle injection. Needle-free provides consistent delivery, eliminates needlestick injuries to healthcare workers, greatly reduces the need for sharps disposal, eliminates needle reuse and the possibility of cross-contamination.
Yes. The cost of an injection with the PharmaJet Precision Delivery Systems is comparable to a needle injection. Reduced dose volume enabled by Tropis intradermal delivery, can decrease vaccine delivery costs by 50%.
No. Partners found “minimal shearing after repeated administration” for DNA vaccines, and for peptide/protein vaccines, “needle-free injection did not affect the particle size.”
No. There is no tissue damage in terms of bruising, but we do suspect there is some tissue “disruption” caused by the injection which actually enables the DNA to get into cells and potentially recruits tissue remodeling cells, and cytokines, etc. that then aid in the immune response to the vaccine.
No serious adverse events have been reported. We also have not seen any increase in injection site reactions compared to needle and syringe.